English name:Paclitaxel
CAS number:33069-62-4
Molecular formula:C47H51NO14
Molecular weight:853.92
Appearance: White crystals.
Melting point 213 °C (dec.)(lit.)
Melting point 213 °C (dec.)(lit.)
Specific optical rotation D20 -49° (methanol)
Boiling point 774.66°C (rough estimate)
Density 0.200
Refractive index -49° (C=1, MeOH)
Flash point 9℃
Storage conditions 2-8°C
Storage conditions 2-8°C
Solubility methanol: 50 mg/mL, clear, colorless
Solubility methanol: 50 mg/mL, clear, colorless
Acidity coefficient (pKa) 11.90±0.20 (Predicted)
form powder
Color white
Water solubility 0.3mg/L(37ºC)
Maximum wavelength (λmax) 227nm(MeOH)(lit.)
Merck 14,6982
Merck 6982
BRN 1420457
Stability Stable. Incompatible with strong oxidizing agents. Flammable.
Indications
It has good effect in treating ovarian cancer and platinum-resistant refractory ovarian cancer and breast cancer. It is also effective in treating prostate cancer, head and neck cancer, esophageal cancer, germ cell tumors, endometrial cance